{"id":211787,"date":"2024-05-26T05:00:16","date_gmt":"2024-05-25T22:00:16","guid":{"rendered":"https:\/\/nawacita.co\/?p=211787"},"modified":"2024-05-24T16:05:55","modified_gmt":"2024-05-24T09:05:55","slug":"metformin-obat-diabetes-yang-ternyata-bisa-lawan-kanker-darah","status":"publish","type":"post","link":"https:\/\/nawacita.co\/index.php\/2024\/05\/26\/metformin-obat-diabetes-yang-ternyata-bisa-lawan-kanker-darah\/","title":{"rendered":"Metformin: Obat Diabetes yang Ternyata Bisa Lawan Kanker Darah?"},"content":{"rendered":"

Metformin: Obat Diabetes yang Ternyata Bisa Lawan Kanker Darah?<\/h1>\n

Jakarta<\/strong>, Nawacita<\/a> <\/strong>– Metformin, obat diabetes yang populer karena sifat penurunan glukosa, bisa bermanfaat dalam mencegah kanker darah, ungkap sebuah studi.<\/p>\n

Dikutip dari Medical Daily, Kamis, studi menunjukkan bahwa penggunaan metformin tidak hanya terbatas pada diabetes, tetapi juga dapat digunakan untuk kondisi seperti penyakit gusi, atrofi otot, COVID-19 jangka panjang, dan untuk mempromosikan penuaan yang sehat.<\/p>\n

\"\"
Metformin.<\/figcaption><\/figure>\n

Potensi mengejutkan dari metformin untuk pencegahan kanker muncul setelah peneliti menemukan hubungan antara penggunaan metformin dan risiko tereduksi terkena neoplasma mieloproliferatif (MPN), jenis langka dari kanker darah yang dapat berkembang menjadi leukemia akut.<\/p>\n

MPN terjadi ketika tubuh membuat terlalu banyak sel darah merah, sel darah putih, atau trombosit. Hal ini menyebabkan masalah pendarahan, risiko stroke berlebihan, serangan jantung, dan kerusakan organ.<\/p>\n

“Tim kami tertarik untuk memahami efek lain yang kita lihat dengan pengobatan yang umum diresepkan seperti metformin.<\/p>\n

Efek antiinflamasi dari metformin menarik minat kami, karena MPN adalah penyakit yang sangat inflamasi. Ini adalah studi pertama yang menyelidiki hubungan antara penggunaan metformin dan risiko terkena MPN,” kata penulis Dr. Anne Stidsholt Roug, dari Rumah Sakit Universitas Aalborg di Denmark.<\/p>\n

Baca Juga: <\/strong>Daging Merah Bisa Picu Kanker Pankreas, Pria Dewasa di Atas 40 Tahun Wajib Tahu!<\/a><\/p>\n

Untuk memahami hubungan antara penggunaan metformin dan diagnosis MPN, para peneliti menggunakan data dari registri kesehatan Denmark, membandingkan 3.816 kasus MPN dengan lebih dari 19 ribu kontrol yang tidak memiliki kondisi tersebut.<\/p>\n

Sedikit lebih dari 8 persen dari kelompok kontrol telah mengonsumsi metformin, dibandingkan dengan 7 persen dari orang yang memiliki MPN. Di antara kelompok kontrol, 2 persen telah mengonsumsi metformin selama lebih dari lima tahun, sementara hanya 1,1 persen yang telah mengonsumsinya dalam jangka panjang pada mereka yang mengembangkan MPN.<\/p>\n

“Hubungan dosis-respons mendukung asosiasi dengan durasi pengobatan yang meningkat, terutama lebih dari lima tahun,” catat para peneliti.<\/p>\n

Para peneliti mencatat bahwa bahkan setelah penyesuaian untuk faktor-faktor confounding potensial, efek perlindungan metformin masih diamati dalam semua subtipe MPN. Efek terbesar terlihat pada subtipe polisitemia vera (PV) dan trombositemia esensial (ET).<\/p>\n

“Hubungan dosis-respons diamati ketika durasi pengobatan kumulatif dianalisis, dan hal ini konsisten dalam analisis stratifikasi jenis kelamin, usia, dan subtipe MPN. Kesimpulannya, penggunaan metformin terkait dengan peluang yang jauh lebih rendah untuk menerima diagnosis MPN, menunjukkan potensi efek pencegahan kanker. Karena desain retrospektif, kausalitas tidak dapat disimpulkan,” katanya sebagai kesimpulan.\u00a0antr<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

Metformin: Obat Diabetes yang Ternyata Bisa Lawan Kanker Darah? Jakarta, Nawacita – Metformin, obat diabetes yang populer karena sifat penurunan glukosa, bisa bermanfaat dalam mencegah kanker darah, ungkap sebuah studi. Dikutip dari Medical Daily, Kamis, studi menunjukkan bahwa penggunaan metformin tidak hanya terbatas pada diabetes, tetapi juga dapat digunakan untuk kondisi seperti penyakit gusi, atrofi […]<\/p>\n","protected":false},"author":4,"featured_media":211791,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6],"tags":[14603,78206,78207,70626],"class_list":{"0":"post-211787","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-healthy","8":"tag-kanker-darah","9":"tag-metformin","10":"tag-obat-diabetes","11":"tag-penyakit-kanker"},"yoast_head":"\nMetformin: Obat Diabetes yang Ternyata Bisa Lawan Kanker Darah?<\/title>\n<meta name=\"description\" content=\"Jakarta, Nawacita - Metformin, obat diabetes yang populer karena sifat penurunan glukosa, bisa bermanfaat dalam mencegah kanker darah\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/nawacita.co\/index.php\/2024\/05\/26\/metformin-obat-diabetes-yang-ternyata-bisa-lawan-kanker-darah\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Metformin: Obat Diabetes yang Ternyata Bisa Lawan Kanker Darah?\" \/>\n<meta property=\"og:description\" content=\"Jakarta, Nawacita - 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