{"id":169610,"date":"2023-06-08T08:10:27","date_gmt":"2023-06-08T01:10:27","guid":{"rendered":"https:\/\/nawacita.co\/?p=169610"},"modified":"2023-06-07T15:21:54","modified_gmt":"2023-06-07T08:21:54","slug":"zat-kimia-di-pemanis-buatan-sukralosa-ternyata-bisa-rusak-dna","status":"publish","type":"post","link":"https:\/\/nawacita.co\/index.php\/2023\/06\/08\/zat-kimia-di-pemanis-buatan-sukralosa-ternyata-bisa-rusak-dna\/","title":{"rendered":"Zat Kimia di Pemanis Buatan Sukralosa Ternyata Bisa Rusak DNA"},"content":{"rendered":"

Zat Kimia di Pemanis Buatan Sukralosa Ternyata Bisa Rusak DNA<\/h1>\n

Jakarta, Nawacita<\/a><\/strong> | Zat kimia di pemanis buatan sukralosa ternyata bisa rusak DNA. Sukralosa merupakan salah satu jenis\u00a0pemanis\u00a0buatan yang sangat populer. Selain memiliki nol kalori, sukralosa juga 600 kali lebih manis dari gula.<\/p>\n

Zat kimia tersebut dikenal dengan nama\u00a0sucralose-6-acetate<\/em>. Zat kimia ini sebenarnya bisa tercipta secara alami ketika\u00a0sukralosa\u00a0sedang dicerna di dalam usus. Saat proses pencernaan tersebut, bakteri usus dapat mengubah sukralosa menjadi senyawa\u00a0sucralose-6-acetate<\/em>.<\/p>\n

Seperti dilansir laman\u00a0Indian Express<\/em>, senyawa larut lemak ini bersifat genotoksik. Artinya,\u00a0sucralose-6-acetate<\/em>\u00a0bisa memecah DNA.<\/p>\n

Menurut studi yang dilakukan tim peneliti dari North Carolina State University,\u00a0sucralose-6-acetate<\/em>\u00a0juga ditemukan di dalam produk-produk sukralosa yang dijual bebas di pasaran. Kandungan\u00a0sucralose-6-acetate<\/em>\u00a0ini sudah ada di dalam\u00a0produk sukralosa\u00a0sebelum\u00a0pemanis buatan\u00a0tersebut dikonsumsi dan dicerna.<\/p>\n

\"ilustrasi<\/a>
ilustrasi pemanis buatan<\/figcaption><\/figure>\n

Tak hanya itu, tim peneliti juga memantau kadar\u00a0sucralose-6-acetate<\/em>\u00a0di dalam produk minuman berpemanis sukralosa. Hasilnya, tim peneliti menemukan bahwa satu porsi minuman berpemanis sukralosa memiliki kadar\u00a0sucralose-6-acetate<\/em>\u00a0yang melebihi ambang batas harian.<\/p>\n

“Dan itu belum termasuk jumlah\u00a0sucralose-6-acetate<\/em>\u00a0yang diproduksi sebagai metabolit saat orang-orang mengonsumsi sukralosa,”\u00a0kata salah satu peneliti dari North Carolina State University dan University of North Carolina, Susan Schiffman.<\/p>\n

Dalam studi yang dipublikasikan pada\u00a0Journal of Toxicology and Environmental Health<\/em>\u00a0ini, tim peneliti turut melakukan beberapa percobaan\u00a0in vitro<\/em>. Melalui percobaan ini, tim peneliti memaparkan sel darah manusia ke\u00a0sucralose-6-acetate<\/em>. Setelah itu, tim peneliti melakukan pemantauan sambil mencari tanda genotoksisitas pada sampel.<\/p>\n

“Kami menemukan bahwa\u00a0sucralose-6-acetate<\/em>\u00a0genotoksik, dan zat kimia ini secara efektif memecah DNA dalam sel yang terpapar,” ujar Schiffman.<\/p>\n

Tim peneliti juga melakukan percobaan lain dengan memaparkan jaringan lapisan dinding usus pada\u00a0sucralose-6-acetate<\/em>. Hasil dari percobaan ini mengindikasikan bahwa paparan\u00a0sucralose-6-acetate<\/em>\u00a0bisa menyebabkan kebocoran usus. Hal ini bisa terjadi karena paparan tersebut menyebabkan kerusakan pada area tempat sel-sel dinding usus saling terhubung.<\/p>\n

Baca Juga:\u00a0Studi: Konsumsi Kangkung Bisa Bantu Kontrol Kadar Gula Darah<\/a><\/strong><\/p>\n

“(Zat kimia) ini membuat dinding usus lebih berpori,”\u00a0kata Schiffman.<\/p>\n

Selain itu, tim peneliti menemukan adanya peningkatan aktivitas pada gen sel-sel usus yang terpapar\u00a0sucralose-6-acetate<\/em>. Peningkatan aktivitas ini berkaitan dengan stres oksidatif, peradangan, serta karsinogenitas.<\/p>\n

Temuan dalam studi terbaru ini mengindikasikan penggunaan sukralosa sebagai pemanis buatan membawa beberapa risiko yang signifikan. Berdasarkan temuan ini, Schiffman menilai perlu adanya peninjauan ulang terkait keamanan dan regulasi sukralosa.<\/p>\n

“Bila tak dilakukan, saya mengimbau orang-orang untuk menghindari produk yang mengandung sukralosa. Ini sesuatu yang seharusnya tak Anda konsumsi,” ujar Schiffman. rpblk<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

Zat Kimia di Pemanis Buatan Sukralosa Ternyata Bisa Rusak DNA Jakarta, Nawacita | Zat kimia di pemanis buatan sukralosa ternyata bisa rusak DNA. Sukralosa merupakan salah satu jenis\u00a0pemanis\u00a0buatan yang sangat populer. Selain memiliki nol kalori, sukralosa juga 600 kali lebih manis dari gula. Zat kimia tersebut dikenal dengan nama\u00a0sucralose-6-acetate. Zat kimia ini sebenarnya bisa tercipta […]<\/p>\n","protected":false},"author":1459,"featured_media":169614,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6],"tags":[59026,46,59027,55938,59023,59025,59022,59024],"class_list":{"0":"post-169610","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-healthy","8":"tag-bahaya-pemanis-buatan","9":"tag-gula","10":"tag-konsumsi-gula-harian","11":"tag-makanan-manis","12":"tag-pemanis-buatan","13":"tag-pemanis-buatan-sukralosa","14":"tag-pemanis-buatan-sukralosa-bisa-rusak-dna","15":"tag-sukralosa"},"yoast_head":"\nZat Kimia di Pemanis Buatan Sukralosa Ternyata Bisa Rusak DNA<\/title>\n<meta name=\"description\" content=\"Jakarta, Nawacita | Zat kimia di pemanis buatan sukralosa ternyata bisa rusak DNA. 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